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Dibenzazepine (iminostilbene) is a chemical compound with two benzene rings fused to an azepine ring. [1] Many pharmaceuticals, such as carbamazepine , oxcarbazepine , and depramine , are based on a dibenzazepine structure.
Historically, "conventional" pharmacotherapy has been used to reduce behaviors and sensitivities associated with ASD. [13] Many such treatments have been prescribed off-label in order to target specific symptoms. [14] Today, medications are primarily prescribed to adults with autism to avoid any adverse effects in the developing brains of children.
Dibenzepin, sold under the brand name Noveril among others, is a tricyclic antidepressant (TCA) used widely throughout Europe for the treatment of depression. [ 2 ] [ 3 ] [ 4 ] It has similar efficacy and effects relative to other TCAs like imipramine but with fewer side effects .
PDD-NOS is not a current part of the Diagnostic and Statistical Manual of Mental Disorders typology (as of the DSM-5), which is the most common diagnostic typology used in the United States. In the still used (though deprecated) ICD-10, it is considered "atypical autism" and "pervasive developmental disorder, unspecified". [8]
Proponents have also claimed that adults may also show signs of sensory processing difficulties and would benefit for sensory processing therapies, [71] although this work has yet to distinguish between those with SPD symptoms alone vs adults whose processing abnormalities are associated with other disorders, such as autism spectrum disorder. [72]
The TCAs are used primarily in the clinical treatment of mood disorders such as major depressive disorder (MDD), dysthymia, and treatment-resistant variants. They are also used in the treatment of a number of other medical disorders, including cyclic vomiting syndrome (CVS) and anxiety disorders such as generalized anxiety disorder (GAD), social phobia (SP) also known as social anxiety ...
Strategies used are designed to address the difficulties faced by all people with autism, and be adaptable to whatever style and degree of support is required. [2] TEACCH methodology is rooted in behavior therapy, more recently combining cognitive elements, [ 4 ] guided by theories suggesting that behavior typical of people with autism results ...
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