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CONN includes a user-friendly GUI to manage all aspects of functional connectivity analyses, [1] including preprocessing of functional and anatomical volumes, [2] elimination of subject-movement and physiological noise, [3] outlier scrubbing, [4] estimation of multiple connectivity and network measures, and population-level hypothesis testing.
Susceptibility weighted imaging (SWI), originally called BOLD venographic imaging, is an MRI sequence that is exquisitely sensitive to venous blood, hemorrhage and iron storage. SWI uses a fully flow compensated, long echo, gradient recalled echo (GRE) pulse sequence to acquire images.
COSMOS assumes a model-free susceptibility distribution and keeps full fidelity to the measured data. This method has been validated extensively in in vitro, ex vivo and phantom experiments. Quantitative susceptibility maps obtained from in vivo human brain imaging also showed high degree of agreement with previous knowledge about brain anatomy ...
The T 2 *-weighted GRE sequence can detect a "middle cerebral artery susceptibility sign", which is a dark linear filling defect that is wider than the corresponding artery on the contralateral side. This sign is 83% sensitive and 100% specific for thrombotic occlusion of the internal carotid artery.
An MRI pulse sequence in magnetic resonance imaging (MRI) is a particular setting of pulse sequences and pulsed field gradients, resulting in a particular image appearance. [ 1 ] A multiparametric MRI is a combination of two or more sequences, and/or including other specialized MRI configurations such as spectroscopy .
However, these techniques are approximate due to phase errors in the MRI data which can rarely be completely controlled (due to imperfect static field shim, effects of spatially selective excitation, signal detection coil properties, motion etc.) or nonzero phase due to just physical reasons (such as the different chemical shift of fat and ...
Dynamic susceptibility contrast: DSC: Measures changes over time in susceptibility-induced signal loss due to gadolinium contrast injection. [20] Provides measurements of blood flow; In cerebral infarction, the infarcted core and the penumbra have decreased perfusion and delayed contrast arrival (pictured). [21] Arterial spin labelling: ASL
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