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Phenytoin (PHT), sold under the brand name Dilantin among others, [1] is an anti-seizure medication. [3] It is useful for the prevention of tonic-clonic seizures (also known as grand mal seizures) and focal seizures, but not absence seizures. [3]
Fetal hydantoin syndrome, also called fetal dilantin syndrome, is a group of defects caused to the developing fetus by exposure to teratogenic effects of phenytoin. Dilantin is the brand name of the drug phenytoin sodium in the United States, commonly used in the treatment of epilepsy .
[2]: 118 The rash may also be one of the potentially lethal severe cutaneous adverse reactions, the DRESS syndrome, Stevens–Johnson syndrome, or toxic epidermal necrolysis. [ 3 ] [ 4 ] Systemic manifestations occur at the time of skin manifestations and include a high number of eosinophils in the blood , liver inflammation , and interstitial ...
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...
Purple glove syndrome (PGS) is a poorly understood skin disease in which the extremities become swollen, discoloured and painful. [1] PGS is potentially serious and may require amputation . PGS is most common among elderly patients and those receiving multiple large intravenous doses of the epilepsy drug phenytoin . [ 2 ]
Its effects last for between four hours and two days. [6] [7] Potentially serious side effects include a decreased level of consciousness and respiratory depressant. [6] There is potential for both abuse and withdrawal following long-term use. [6] It may also increase the risk of suicide. [6]
These signs and symptoms are not side effects of the drugs taken which occur during short term use. DIL occurs over long-term and chronic use of the medications listed below. While these symptoms are similar to those of systemic lupus erythematosus , they are generally not as severe unless they are ignored which leads to more harsh symptoms ...
Common side effects of levetiracetam include sleepiness, dizziness, feeling tired, and aggression. [8] Severe side effects may include psychosis, suicide, and allergic reactions such as Stevens–Johnson syndrome or anaphylaxis. [8] Levetiracetam is the S-enantiomer of etiracetam. [11] It acts as a synaptic vesicle glycoprotein 2A (SV2A) ligand ...