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Much research has been done into the use of a rat model to show how Borna virus infection, [17] [18] exposure to valproic acid in utero, [19] and maternal immune activation [20] may cause autism. Another goal of the use of rodent models to study autism is to identify the mechanism by which autism develops in humans. [ 1 ]
The underconnectivity theory of autism posits that autistic people tend to have fewer high-level neural connections and less global synchronization, along with an excess of low-level processes. [31] Functional connectivity studies have found both hypo- and hyperconnectivity in brains of autistic people. [ 32 ]
Proponents of the imprinted brain hypothesis argue that since it is uncertain if a woman's other and future children have and will have the same father, as well as the father generally having lower parental investment, it may be in the father's reproductive interest for his child to use more of the mother's resources than other children, while it may be in the mother's interest for a child to ...
However, because of the multigene involvement in autism, the MECP2 gene has only been identified as a vulnerability factor in autism. [63] The most current model illustrating MECP2 is known as the transcriptional activator model. Another potential molecular convergence involves the early growth response gene-2 (EGR2). [60]
Research using an animal model of obsessive-compulsive disorder employed a standardized paradigm where the behavior of rats in a large open field was video recorded for 55 min on each test. Rat Macroscopic Video Obsessive-compulsive disorder No [2] Allen Brain Atlas: Atlas, stained sections from brains showing development and gene expression
To probe insular neural circuits, Gogolla and her lab use in vivo two-photon calcium imaging to record neural activity while mice are processing emotionally relevant stimuli, and they further use innovative behavioral assays, optogenetic techniques, and machine learning algorithms to link neural activity to behavior, manipulate neural circuits ...
Educational neuroscience (or neuroeducation, [1] a component of Mind Brain and Education) is an emerging scientific field that brings together researchers in cognitive neuroscience, developmental cognitive neuroscience, educational psychology, educational technology, education theory and other related disciplines to explore the interactions between biological processes and education.
The dynamic-maturational model of attachment and adaptation (DMM) is a biopsychosocial model describing the effect attachment relationships can have on human development and functioning. It is especially focused on the effects of relationships between children and parents and between reproductive couples.