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Copy number variation (CNV) is a phenomenon in which sections of the genome are repeated and the number of repeats in the genome varies between individuals. [1] Copy number variation is a type of structural variation: specifically, it is a type of duplication or deletion event that affects a considerable number of base pairs. [2]
Copy number analysis is the process of analyzing data produced by a test for DNA copy number variation in an organism's sample. One application of such analysis is the detection of chromosomal copy number variation that may cause or may increase risks of various critical disorders.
Query by Example (QBE) is a database query language for relational databases. It was devised by Moshé M. Zloof at IBM Research during the mid-1970s, in parallel to the development of SQL . [ 1 ] It is the first graphical query language, using visual tables where the user would enter commands, example elements and conditions.
Multiplex ligation-dependent probe amplification (MLPA) is a variation of the multiplex polymerase chain reaction that permits amplification of multiple targets with only a single primer pair. [1] It detects copy number changes at the molecular level, and software programs are used for analysis.
For example, pBR322 is a medium copy number plasmid (~20 copies/cell) from which several high copy number cloning vectors (>100 copies/cell) have been derived by mutagenesis, such as the well known pUC series. [1] This delivers the convenience of high plasmid DNA yields but the additional burden of the high copy number restricts the plasmid size.
Discounted cumulative gain (DCG) is a measure of ranking quality in information retrieval. It is often normalized so that it is comparable across queries, giving Normalized DCG (nDCG or NDCG) . NDCG is often used to measure effectiveness of search engine algorithms and related applications.
The SQL/Schemata, or Information and Definition Schemas, part of the SQL standard is defined by ISO/IEC 9075-11:2008. SQL/Schemata defines the information schema and definition schema , providing a common set of tools to make SQL databases and objects self-describing.
SQL-92 was the third revision of the SQL database query language. Unlike SQL-89, it was a major revision of the standard. Aside from a few minor incompatibilities, the SQL-89 standard is forward-compatible with SQL-92. The standard specification itself grew about five times compared to SQL-89.