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Since then many discoveries have been made. Nephrotic syndrome occurs when there is a breakdown of the glomerular filtration barrier. The podocytes form one layer of the filtration barrier. Genetic mutations can cause podocyte dysfunction leading to an inability of the filtration barrier to restrict urinary protein loss.
The human urinary system, also known as the urinary tract or renal system, consists of the kidneys, ureters, bladder, and the urethra. The purpose of the urinary system is to eliminate waste from the body, regulate blood volume and blood pressure, control levels of electrolytes and metabolites , and regulate blood pH .
Bowman's space (or "urinary space", or "capsular space")—Between the visceral and parietal layers, into which the filtrate enters after passing through the filtration slits. [1] Visceral layer—Lies just above the thickened glomerular basement membrane and is made of podocytes. Beneath the visceral layer lie the glomerular capillaries.
Like the bony pelvis, the renal pelvis (/ ˈ r iː n əl ˈ p ɛ l v ɪ s /) gets its English name via Neo-Latin from the older Latin word pelvis, "basin", as in "wash basin". [4] In both cases the name reflects the shape of the structure, and in the case of the renal pelvis, it also reflects the function.
Renal corpuscle showing glomerulus and glomerular capillaries Figure 2: (a) Diagram of the juxtaglomerular apparatus: it has specialized cells working as a unit which monitor the sodiujuxtaglomerular apparatus: it has three types of specm content of the fluid in the distal convoluted tubule (not labelled - it is the tubule on the left) and adjust the glomerular filtration rate and the rate of ...
The nephron is the minute or microscopic structural and functional unit of the kidney.It is composed of a renal corpuscle and a renal tubule.The renal corpuscle consists of a tuft of capillaries called a glomerulus and a cup-shaped structure called Bowman's capsule.
In monotremes, the ureters open into the urogenital sinus, which is connected to the urinary bladder and cloaca, [65] and urine is excreted into the cloaca instead of the urethra. [66] [65] Structurally, kidneys vary between mammals. [67] Which structural type a particular species will have depends mainly on the body mass of the species. [68]
Unlike the urinary bladder of vertebrates, the urinary bladder of crustaceans both stores and modifies urine. [50] The bladder consists of two sets of lateral and central lobes. The central lobes sit near the digestive organs and the lateral lobes extend along the front and sides of the crustacean's body cavity. [50]