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Convulsive therapy was introduced in 1934 by Hungarian neuropsychiatrist Ladislas J. Meduna who, believing mistakenly that schizophrenia and epilepsy were antagonistic disorders, induced seizures first with camphor and then metrazol (cardiazol). [14] [15] Meduna is thought to be the father of convulsive therapy. [16]
An early clinical trial by Eli Lilly of the drug LY2140023 has shown potential for treating schizophrenia without the weight gain and other side-effects associated with conventional anti-psychotics. [ 23 ] [ 24 ] [ 25 ] A trial in 2009 failed to prove superiority over placebo or Olanzapine , but Lilly explained this as being due to an ...
Perhaps their most famous and influential publication was Towards a Theory of Schizophrenia (1956), [1] which introduced the concept of the Double Bind, and helped found Family Therapy. [2] One of the project's first locations was the Menlo Park VA Hospital, which was chosen because of Bateson's previous work there as an ethnologist. [3]
Like many new medical treatments for diseases previously considered incurable, depictions of insulin coma therapy in the media were initially favorable. In the 1940 film Dr. Kildare's Strange Case, young Kildare uses the new "insulin shock cure for schizophrenia" to bring a man back from insanity. The film dramatically shows a five-hour ...
The outcomes paradox (otherwise known as the "better prognosis hypothesis") is the observation that patients with schizophrenia in developing countries benefit much more from therapy than those in developed countries. This is surprising because the reverse holds for most diseases: "the richer and more developed the country, the better the ...
Applications of antipsychotic drugs in the treatment of schizophrenia include prophylaxis for those showing symptoms that suggest that they are at high risk of developing psychosis; treatment of first-episode psychosis; maintenance therapy (a form of prophylaxis, maintenance therapy aims to maintain therapeutic benefit and prevent symptom ...
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