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A sarcoma is a malignant tumor, a type of cancer that arises from cells of mesenchymal (connective tissue) origin. [1] [2] Connective tissue is a broad term that includes bone, cartilage, muscle, fat, vascular, or other structural tissues, and sarcomas can arise in any of these types of tissues.
In the United States there has been an increase in the 5-year relative survival rate between people diagnosed with cancer in 1975-1977 (48.9%) and people diagnosed with cancer in 2007-2013 (69.2%); these figures coincide with a 20% decrease in cancer mortality from 1950 to 2014. [8]
Extra-osseous Ewing’s sarcoma accounts for roughly 20% of Ewing’s sarcoma cases, and most commonly occurs in the glutes, shoulders, and arms. The presentation is nonspecific, with most patients first reporting a painful mass. Initial workup is similar to Ewing’s sarcoma of bone, beginning with imaging.
Classic Kaposi sarcoma most commonly appears early on the toes and soles as reddish, violaceous, or bluish-black macules and patches that spread and coalesce to form nodules or plaques. [35]: 599 A small percentage of these patients may have visceral lesions. In most cases the treatment involves surgical removal of the lesion.
Ewing sarcomas represent 16% of primary bone sarcomas. [14] In the United States, they are most common in the second decade of life, [14] with a rate of 0.3 cases per million in children under 3 years of age, and as high as 4.6 cases per million in adolescents aged 15–19 years. Nearly 80% of patients are aged less than 20 years of age. [45]
Chondrosarcoma is a bone sarcoma, a primary cancer composed of cells derived from transformed cells that produce cartilage. [1] A chondrosarcoma is a member of a category of tumors of bone and soft tissue known as sarcomas. About 30% of bone sarcomas are chondrosarcomas. [2] It is resistant to chemotherapy and radiotherapy. Unlike other primary ...
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