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Collagen alpha-2(V) chain is a protein that in humans is encoded by the COL5A2 gene. [5] [6] This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains.
The collagen protein is composed of a triple helix, which generally consists of two identical chains (α1) and an additional chain that differs slightly in its chemical composition (α2). [23] The amino acid composition of collagen is atypical for proteins, particularly with respect to its high hydroxyproline content.
Collagen alpha-1(VIII) chain is a protein that in humans is encoded by the COL8A1 gene. [5] [6] This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a ...
1292 12834 Ensembl ENSG00000142173 ENSMUSG00000020241 UniProt P12110 Q02788 RefSeq (mRNA) NM_001849 NM_058174 NM_058175 NM_146007 NM_001347207 RefSeq (protein) NP_001840 NP_478054 NP_478055 NP_001334136 NP_666119 Location (UCSC) Chr 21: 46.1 – 46.13 Mb Chr 10: 76.43 – 76.46 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Collagen alpha-2(VI) chain is a protein that in humans is ...
Collagen, type I, alpha 1, also known as alpha-1 type I collagen, is a protein that in humans is encoded by the COL1A1 gene. COL1A1 encodes the major component of type I collagen , the fibrillar collagen found in most connective tissues , including cartilage .
Collagen alpha-3(VI) chain is a protein that in humans is encoded by the COL6A3 gene. [ 5 ] [ 6 ] [ 7 ] This protein is an alpha chain of type VI collagen that aids in microfibril formation. [ 8 ] As part of type VI collagen, this protein has been implicated in Bethlem myopathy, Ullrich congenital muscular dystrophy (UCMD), and other diseases ...