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Ectopic expression is an abnormal gene expression in a cell type, tissue type, or developmental stage in which the gene is not usually expressed. [ 1 ] [ 2 ] The term ectopic expression is predominantly used in studies using metazoans, especially in Drosophila melanogaster for research purposes.
Gene conversion is the process by which one DNA sequence replaces a homologous sequence such that the sequences become identical after the conversion. [1] Gene conversion can be either allelic, meaning that one allele of the same gene replaces another allele, or ectopic, meaning that one paralogous DNA sequence converts another.
Promiscuous gene expression (PGE), formerly referred to as ectopic expression, is a process specific to the thymus that plays a pivotal role in the establishment of central tolerance.
Gene duplications can arise as products of several types of errors in DNA replication and repair machinery as well as through fortuitous capture by selfish genetic elements. Common sources of gene duplications include ectopic recombination, retrotransposition event, aneuploidy, polyploidy, and replication slippage. [1]
Ectopic recombination is an atypical form of recombination in which a crossing over takes place between two homologous DNA sequences located at non-allelic chromosomal positions. Such recombination often results in dramatic chromosomal rearrangement , which is generally harmful to the organism. [ 1 ]
An ectopic pregnancy is a common complication that can be life-threatening to the mother if left untreated. Here's what you need to know.
Megan Fox has revealed that she had an ectopic pregnancy years before experiencing a miscarriage.. During an interview with Women’s Wear Daily (WWD), published on 29 November, the 37-year-old ...
Antennapedia (abbreviated Antp) is a Hox gene first discovered in Drosophila which controls the formation of legs during development. Loss-of-function mutations in the regulatory region of this gene result in the development of the second leg pair into ectopic antennae. By contrast gain-of-function alleles convert antennae into ectopic legs. [1]