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Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain. [1] [2] If there is decreased secretion of one specific pituitary hormone, the condition is known as selective hypopituitarism. [3]
CHH can be diagnosed in the male neonate with cryptorchidism (maldescended testes) and a micropenis as signs of GnRH deficiency. [4] There are no clear signs of CHH in female neonates. [4] Another clinical sign of CHH, more specifically Kallmann syndrome, is a lack of a sense of smell due to the altered migration of GnRH neurons on the ...
Signs and symptoms [ edit ] Autoimmune hypophysitis can lead to deficiencies in one or more pituitary hormones, causing central diabetes insipidus if the posterior pituitary gland is affected as well as central adrenal insufficiency and central hypothyroidism if the anterior pituitary gland is affected. [ 1 ]
Sheehan's syndrome, also known as postpartum pituitary gland necrosis, occurs when the pituitary gland is damaged due to significant blood loss and hypovolemic shock (ischemic necrosis) or stroke, originally described during or after childbirth leading to decreased functioning of the pituitary gland (hypopituitarism). [1]
Poor pituitary production of LH is thought to be implicated in obesity-associated testosterone deficiency. One study revealed that altering a BMI from 30 to 25 kg/m2 could result in a 13 percent ...
Testing serum LH and FSH levels are often used to assess hypogonadism in women, particularly when menopause is believed to be happening. These levels change during a woman's normal menstrual cycle, so the history of having ceased menstruation coupled with high levels aids the diagnosis of being menopausal.