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Studies in male mouse meiosis have shown that after DNA damaging treatments like gamma irradiation, two types of repair responses occur depending on the meiotic stage: [5] From leptotene to early pachytene, exogenous DNA damage triggers widespread presence of the repair protein gammaH2AX in the nucleus, associated with homologous recombination ...
Zygotene (from greek "paired threads" [1]) is the second stage of prophase I during meiosis, the specialized cell division that reduces the chromosome number by half to produce haploid gametes. It follows the Leptotene stage and is followed by Pachytene stage.
This is an accepted version of this page This is the latest accepted revision, reviewed on 19 December 2024. Cell division producing haploid gametes For the figure of speech, see Meiosis (figure of speech). For the process whereby cell nuclei divide to produce two copies of themselves, see Mitosis. For excessive constriction of the pupils, see Miosis. For the parasitic infestation, see Myiasis ...
As it occurs after G2 of interphase, DNA has been already replicated when prophase begins. [1] Fluorescence microscope image of two mouse cell nuclei in prophase (scale bar is 5 μm). [2] Prophase (from Ancient Greek προ- 'before' and φάσις (phásis) 'appearance') is the first stage of cell division in both mitosis and meiosis.
During the phase of meiosis labeled “interphase s” in the meiosis diagram there is a round of DNA replication, so that each of the chromosomes initially present is now composed of two copies called chromatids. These chromosomes (paired chromatids) then pair with the homologous chromosome (also paired chromatids) present in the same nucleus ...
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McClintock used the prophase and metaphase stages of mitosis to describe the morphology of corn's chromosomes, and later showed the first ever cytological demonstration of crossing over in meiosis. Working with student Harriet Creighton, McClintock also made significant contributions to the early understanding of codependency of linked genes.
When meiosis I is completed, one secondary oocyte and one polar body is created. Primary oocytes have been created in late fetal life. This is the stage where immature ova spend most of their lifetime, more specifically in diplotene of prophase I of meiosis. The halt is called dictyate.