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A formulation of over-the-counter antioxidant supplements may help prevent the progression of dry age-related macular degeneration, a new study finds.
Macular degeneration is the leading cause of severe, irreversible vision loss in older adults. [ 91 ] [ 92 ] Several risk factors have been linked to macular degeneration, including family history, genetics, hypercholesterolemia, hypertension, sunlight exposure and lifestyle (smoking and diet).
The anti-oxidants and zinc supplements only reduced the risk of progression to wet macular degeneration. Those that benefited from the dietary supplements included those with intermediate-stage AMD and those with advanced AMD in one eye only. The supplements had no significant effect on the development or progression of cataracts.
[46] [needs update] Including lutein and zeaxanthin supplements in with a multivitamin does not improve progression of macular degeneration. [46] The need for high-quality studies looking at the safety of taking multivitamins has been highlighted. [46] According to the Harvard School of Public Health: "... many people don't eat the healthiest ...
The incidence of age-related macular degeneration and its associated features increases with age and is low in people <55 years of age. [101] Smoking is the strongest modifiable risk factor. [102] As of 2008, age-related macular degeneration accounts for more than 54% of all vision loss in the white population in the US. [103]
The predominant cause of nutritional optic neuropathy is thought to be deficiency of B-complex vitamins, particularly thiamine [2] (vitamin B 1), cyanocobalamin (vitamin B 12) and recently copper. [3] Deficiency of pyridoxine (vitamin B 6), niacin (vitamin B 3), riboflavin (vitamin B 2), and/or folic acid also seems to play a role. Those ...