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Nitrofurantoin, sold under the brand name Macrobid among others, is an antibacterial medication of the nitrofuran class used to treat urinary tract infections (UTIs), although it is not as effective for kidney infections. [16] It is taken by mouth. [16] Common side effects include nausea, loss of appetite, diarrhea, and headaches. [16]
A disulfiram-like drug is a drug that causes an adverse reaction to alcohol leading to nausea, vomiting, flushing, dizziness, throbbing headache, chest and abdominal discomfort, and general hangover-like symptoms among others.
Many patients will not develop these side effects, although there is still a significant possibility of risks associated with Antipsychotic usage. The percentage of patients affected by side effects like Tardive dyskinesia is significantly high and estimated to be a 20-50% prevalence. [1] [2]
flesh eating infections (necrotizing fasciits) is often caused by streptococcus pyogenes or staphylococcus sp. i don't think this is the appropriate forum for a discussion on treatment options, but nitrofurantoin does not get absorbed very well and doesn't penetrate most of the tissues associated with staph infections.
Pyelonephritis occurs between 20 and 30 times less frequently. [4] They are the most common cause of hospital-acquired infections accounting for approximately 40%. [ 115 ] Rates of asymptomatic bacteria in the urine increase with age from two to seven percent in women of child-bearing age to as high as 50% in elderly women in care homes. [ 42 ]
Chronic bacterial prostatitis is thought to be caused by ascending urethral infection and by reflux into the ejaculatory duct or prostatic ducts. [7] Risk factors for chronic bacterial prostatitis include functional or anatomic abnormalities, catheterization, prostate biopsy or urethritis (due to sexually transmitted infections), and unprotected penetrative anal sex. [7]
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[20] Two regions of the sulfonamide antibiotic chemical structure are implicated in the hypersensitivity reactions associated with the class. The first is the N1 heterocyclic ring, which causes a type I hypersensitivity reaction.