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A lung nodule or pulmonary nodule is a relatively small focal density in the lung. A solitary pulmonary nodule (SPN) or coin lesion, [1] is a mass in the lung smaller than three centimeters in diameter. A pulmonary micronodule has a diameter of less than three millimetres. [2] There may also be multiple nodules. One or more lung nodules can be ...
Date: 15 November 2017: Source (2017). "Evaluation of the solitary pulmonary nodule: size matters, but do not ignore the power of morphology". Insights into Imaging 9 (1): 73–86.
English: Original caption: Complex lesion in the right upper lobe in a 61-year heavy smoker. Axial CT-image in lung window setting shows a 2.6 cm lesion with spiculated morphology, pleural tags and centrally small lucent foci, corresponding to the so-called “bubble-like-lucencies”.
AAH is a pre-malignant cause of nodular GGO and is more commonly associated with lower attenuation on CT and smaller nodule size (<10 mm) compared to adenocarcinoma. [10] In addition, AAH often lacks the solid features and spiculated appearance that are often associated with malignant growths. [9]
Minimally invasive adenocarcinoma of the lung (MIA) is defined as a small (≤3 cm), solitary tumour with predominant alveolar epithelial appearance (lepidic growth), as in situ adenocarcinoma of the lung, with a zone of focal invasion of the stroma with a size inferior to 5 mm. [1] For MIA—as with adenocarcinoma in situ—, the prognosis is near 100% survival.
The lesion itself serves as a biomarker, but the minute details of the lesion serve as biomarkers as well, and can collectively be used to assess the risk of neoplasm. Some of the imaging biomarkers used in lung nodule assessment include size, spiculation, calcification, cavitation, location within the lung, rate of growth, and rate of metabolism.
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