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  2. Sacubitril/valsartan - Wikipedia

    en.wikipedia.org/wiki/Sacubitril/valsartan

    Sacubitril/valsartan, sold under the brand name Entresto among others, is a fixed-dose combination medication for use in heart failure. It consists of the neprilysin inhibitor sacubitril and the angiotensin receptor blocker valsartan .

  3. Sacubitril - Wikipedia

    en.wikipedia.org/wiki/Sacubitril

    Sacubitril is a prodrug that is activated to sacubitrilat (LBQ657) by de-ethylation via esterases. [2] Sacubitrilat inhibits the enzyme neprilysin, [3] which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure–lowering peptides that work mainly by reducing blood volume. [4]

  4. How much does Entresto cost with Medicare? - AOL

    www.aol.com/much-does-entresto-cost-medicare...

    Entresto helps manage chronic heart failure by reducing the effort necessary for the heart to pump blood around the body. This article explains how much a person with Medicare Part D typically ...

  5. Valsartan - Wikipedia

    en.wikipedia.org/wiki/Valsartan

    Other serious side effects may include kidney problems, low blood pressure, and angioedema. [8] Use in pregnancy may harm the baby and use when breastfeeding is not recommended. [9] It is an angiotensin II receptor antagonist and works by blocking the effects of angiotensin II. [8] Valsartan was patented in 1990, and came into medical use in ...

  6. Novartis loses initial bid to block generic of best-selling ...

    www.aol.com/news/novartis-loses-initial-bid...

    The judge also rejected Novartis' argument that a ruling against the company would cause "irreparable harm" by triggering a wave of generic Entresto launches by other drugmakers.

  7. Novartis lifts profit forecast for second time on Cosentyx ...

    www.aol.com/news/novartis-raises-2024-profit...

    Swiss drugmaker Novartis raised its 2024 earnings guidance for the second time on Thursday, driven by a gain in prescriptions for drugs including heart failure treatment Entresto and arthritis ...

  8. Berotralstat - Wikipedia

    en.wikipedia.org/wiki/Berotralstat

    The most common side effects include abdominal pain, vomiting, diarrhea, back pain, and heartburn. [4] Berotralstat was approved for medical use in the United States in December 2020, [3] [4] [9] and in the European Union in April 2021. [5]

  9. Mayo Clinic - Wikipedia

    en.wikipedia.org/wiki/Mayo_Clinic

    Mayo Clinic is a nonprofit hospital system with campuses in Rochester, Minnesota; Scottsdale and Phoenix, Arizona; and Jacksonville, Florida. [22] [23] Mayo Clinic employs 76,000 people, including more than 7,300 physicians and clinical residents and over 66,000 allied health staff, as of 2022. [5]