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Despite the varying grades of PVL and cerebral palsy, affected infants typically begin to exhibit signs of cerebral palsy in a predictable manner. Typically, some abnormal neurological signs (such as those previously mentioned) are visible by the third trimester of pregnancy (28 to 40 weeks after conception), and definitive signs of cerebral ...
Cerebral palsy is defined as "a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain."
Colpocephaly is a cephalic disorder involving the disproportionate enlargement of the occipital horns of the lateral ventricles and is usually diagnosed early after birth due to seizures. It is a nonspecific finding and is associated with multiple neurological syndromes , including agenesis of the corpus callosum , Chiari malformation ...
Children who experienced many complications during birth, such as, prematurity, insufficient oxygen, low birthweight, aspiration, head injury, or bleeding in the brain have a greater risk of developing spastic quadriplegia. Children whose mothers were ill during the pregnancy or did not receive adequate nutrition are also more likely to develop ...
Brain damage may be caused by a number of factors, including fetal malformation due to genetic mutation or exposure to toxins, intrauterine hypoxia, or physical trauma during delivery. [12] Cerebral palsy is one example of brain damage incurred before or during delivery; about 10,000 children are diagnosed with cerebral palsy every year. [13]
A large study followed children born between 22 and 25 weeks until the age of 6 years old. Of these children, 46% had moderate to severe disabilities such as cerebral palsy, vision or hearing loss and learning disabilities, 34% had mild disabilities, and 20% had no disabilities; 12% had disabling cerebral palsy. [192]
Fetal alcohol spectrum disorders are a group of conditions caused prior to birth that can occur in a person whose mother drank alcohol during pregnancy. Cerebral palsy is a group of disorders that affect a person's ability to move and maintain balance and posture. They are the most common motor disability in childhood.
Infections like chorioamnionitis cause an infection in the maternal blood, commonly leading to premature birth and the newborn experiencing brain damage, meningitis, or death. [29] Other infections include neonatal sepsis, where the immune system reacts by affecting their organs and tissues resulting in meningitis, seizures, and cerebral palsy ...