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[2] Sepsis requires immediate treatment with intravenous fluids and antimicrobial medications. [1] [5] Ongoing care and stabilization often continues in an intensive care unit. [1] If an adequate trial of fluid replacement is not enough to maintain blood pressure, then the use of medications that raise blood pressure becomes necessary. [1]
Septic shock is a result of a systemic response to infection or multiple infectious causes. The precipitating infections that may lead to septic shock if severe enough include but are not limited to appendicitis, pneumonia, bacteremia, diverticulitis, pyelonephritis, meningitis, pancreatitis, necrotizing fasciitis, MRSA and mesenteric ischemia.
Distributive shock is different from the other three categories of shock in that it occurs even though the output of the heart is at or above a normal level. [2] The most common cause is sepsis leading to a type of distributive shock called septic shock, a condition that can be fatal. [1]
Second-degree atrioventricular block (AV block) is a disease of the electrical conduction system of the heart.It is a conduction block between the atria and ventricles.The presence of second-degree AV block is diagnosed when one or more (but not all) of the atrial impulses fail to conduct to the ventricles due to impaired conduction.
In an AV block, this electrical signal is either delayed or completely blocked. When the signal is completely blocked, the ventricles produce their own electrical signal to control the heart rate. The heart rate produced by the ventricles is much slower than that produced by the SA node. [1]
Finally, it’s worth pointing out that the electrical conduction system is kind of like the electrical wiring in the walls of a house, so it makes sense that diseases of the heart muscle walls - cardiomyopathies, and inflammation of the heart muscle or myocarditis, can both cause heart block.
First degree AV block does not generally cause any symptoms, but may progress to more severe forms of heart block such as second- and third-degree atrioventricular block. It is diagnosed using an electrocardiogram , and is defined as a PR interval greater than 200 milliseconds. [ 1 ]
Early-onset neonatal sepsis is found to be 0.77 to 1 per 100,000 live births in the U.S. In premature babies, the incidence and mortality rates are higher due to the weakness of their immune system. For infants with low birth weight, cases of early-onset sepsis is found to be about 26 per 1,000 and 8 per 1,000 live births.