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In accordance with this, drugs that affect 5-HT-containing cells or 5-HT receptors are effective treatments for numerous indications, including depression, anxiety, obesity, nausea, and migraine. Because serotonin and the related hormone melatonin are involved in promoting sleep, they counterbalance the wake-promoting action of increased ...
[12] [15] The United States Food and Drug Administration has granted "breakthrough therapy" status, which expedites the potential approval of promising drug therapies, [note 2] to psychedelic therapies using psilocybin (for treatment-resistant depression and major depressive disorder) [6] and MDMA (for post-traumatic stress disorder). [17]
[18] [19] Studies conducted using psilocybin in a psychotherapeutic setting reveal that psychedelic drugs may assist with treating depression, alcohol addiction, and nicotine addiction. [11] [20] Although further research is needed, existing results suggest that psychedelics could be effective treatments for certain forms of psychopathology.
Treatment usually entails gradually reducing the dosage over a period of weeks or several months, depending on the individual, dosage, and length of time the drug has been taken. If this approach fails, a crossover to a benzodiazepine equivalent dose of a long-acting benzodiazepine (such as chlordiazepoxide or, more preferably, diazepam ) can ...
A 2012 meta-analysis of fluoxetine and venlafaxine concluded that statistically and clinically significant treatment effects were observed for each drug relative to placebo irrespective of baseline depression severity; some of the authors however disclosed substantial relationships with pharmaceutical industries. [14]
An analysis published Wednesday in medical journal The BMJ indicates that several types of exercise were "superior" to antidepressants for treating depression.. The study included 218 randomized ...
Mescaline has a wide array of suggested medical usage, including treatment of depression, anxiety, PTSD, [35] and alcoholism. [36] However, its status as a Schedule I controlled substance in the Convention on Psychotropic Substances limits availability of the drug to researchers. Because of this, very few studies concerning mescaline's activity ...
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.