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  2. Phosphofructokinase 2 - Wikipedia

    en.wikipedia.org/wiki/Phosphofructokinase_2

    In enzymology, a 6-phosphofructo-2-kinase (EC 2.7.1.105) is an enzyme that catalyzes the chemical reaction: ATP + beta-D-fructose 6-phosphate ADP + beta-D-fructose 2,6-bisphosphate [16] Thus, the kinase domain hydrolyzes ATP to phosphorylate the carbon-2 of fructose-6-phosphate, producing Fru-2,6-P 2 and ADP.

  3. 1-phosphofructokinase - Wikipedia

    en.wikipedia.org/wiki/1-phosphofructokinase

    In enzymology, 1-phosphofructokinase (EC 2.7.1.56) is an enzyme that catalyzes the chemical reaction. ATP + D-fructose 1-phosphate → ADP + D-fructose 1,6-bisphosphate. Thus, the two substrates of this enzyme are ATP and D-fructose 1-phosphate, whereas its two products are ADP and D-fructose 1,6-bisphosphate. The enzyme was first described and ...

  4. Phosphofructokinase - Wikipedia

    en.wikipedia.org/wiki/Phosphofructokinase

    PFK exists as a homotetramer in bacteria and mammals (where each monomer possesses 2 similar domains) and as an octomer in yeast (where there are 4 alpha- (PFK1) and 4 beta-chains (PFK2), the latter, like the mammalian monomers, possessing 2 similar domains [3]). This protein may use the morpheein model of allosteric regulation. [5]

  5. Glycolysis - Wikipedia

    en.wikipedia.org/wiki/Glycolysis

    d -Glucose + 2 [NAD] + + 2 [ADP] + 2 [P] i 2 × Pyruvate 2 × + 2 [NADH] + 2 H + + 2 [ATP] + 2 H 2 O Glycolysis pathway overview The use of symbols in this equation makes it appear unbalanced with respect to oxygen atoms, hydrogen atoms, and charges. Atom balance is maintained by the two phosphate (P i) groups: Each exists in the form of a hydrogen phosphate anion, dissociating to contribute ...

  6. Fructose 2,6-bisphosphate - Wikipedia

    en.wikipedia.org/wiki/Fructose_2,6-bisphosphate

    Fru-2,6-P 2 strongly activates glucose breakdown in glycolysis through allosteric modulation (activation) of phosphofructokinase 1 (PFK-1).Elevated expression of Fru-2,6-P 2 levels in the liver allosterically activates phosphofructokinase 1 by increasing the enzyme’s affinity for fructose 6-phosphate, while decreasing its affinity for inhibitory ATP and citrate.

  7. Phosphofructokinase 1 - Wikipedia

    en.wikipedia.org/wiki/Phosphofructokinase_1

    Phosphofructokinase-1 (PFK-1) is one of the most important regulatory enzymes (EC 2.7.1.11) of glycolysis. It is an allosteric enzyme made of 4 subunits and controlled by many activators and inhibitors. PFK-1 catalyzes the important "committed" step of glycolysis, the conversion of fructose 6-phosphate and ATP to fructose 1,6-bisphosphate and ...

  8. NFL playoff schedule: Dates, times, TV info for wild-card ...

    www.aol.com/nfl-playoff-schedule-dates-times...

    The NFL playoff schedule is about to be set, with the wild-card dates and times for every matchup to be revealed during Week 18.

  9. Fructose 1,6-bisphosphatase - Wikipedia

    en.wikipedia.org/wiki/Fructose_1,6-bisphosphatase

    D-fructose 1,6-bisphosphate + H 2 O = D-fructose 6-phosphate + phosphate Phosphofructokinase (EC 2.7.1.11) catalyses the reverse conversion of fructose 6-phosphate to fructose-1,6-bisphosphate, but this is not just the reverse reaction, because the co-substrates are different (and so thermodynamic requirements are not violated).