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A painkiller from Vertex was shown to significantly reduce pain in post-surgery and other patients in late-stage clinical trials. This experimental painkiller could be alternative to addictive opioids
A 2018 BMJ study of 568,612 patients who took prescription opioids following surgery found that 5,906, or 1 percent, showed documented signs of "opioid misuse" during the course of the study ...
Vertex Pharmaceuticals recently reported positive results for a non-opioid painkiller, one of several medications the Boston-based drugmaker has been developing for various forms of pain.
Tapentadol is a novel opioid that displays high affinity and selectivity for the μ-opioid receptor; In a human liability pharmacology study conducted by the sponsor, it was found that tapentadol displays a high abuse potential similar to hydromorphone , a controlled substance with a similar risk of abuse, misuse and diversion; and
In April 2019 the U.S. Food and Drug Administration announced the launch of a new education campaign to help Americans understand the important role they play in removing and properly disposing of unused prescription opioids from their homes. This new initiative is part of the FDA's continued efforts to address the nationwide opioid crisis (see ...
AT-121 is an experimental analgesic.It was designed to be bifunctional, acting as an agonist at both the μ-opioid receptor and the nociceptin receptor. [1] The interaction with the nociceptin receptor is expected to block the abuse and dependence-related side effects that are typical of opioids. [2]
(Reuters) -Vertex Pharmaceuticals' experimental drug reduced acute, post-surgical pain without the risk of addiction, a major milestone in the company's decades-long efforts to bring a non-opioid ...
Latigo Biotherapeutics emerged from stealth mode on Wednesday and said it had raised $135 million in series A funding to advance clinical trials of its non-opioid pain treatments, including a drug ...