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ZMapp was first used during the 2014 West Africa Ebola Virus outbreak, having not previously undergone any human clinical trials to determine its efficacy or potential risks. [3] By October 2014, the United States Food and Drug Administration had approved the use of several experimental drugs, including ZMapp, to be used on patients infected ...
The Ervebo vaccine, developed by Merck, is a single-dose vaccine. It works by using a modified virus to produce antibodies against Ebola, equipping the immune system to recognise and neutralise ...
Ebola vaccines are vaccines either approved or in development to prevent Ebola. As of 2022, there are only vaccines against the Zaire ebolavirus. The first vaccine to be approved in the United States was rVSV-ZEBOV in December 2019. [9] [10] It had been used extensively in the Kivu Ebola epidemic under a compassionate use protocol. [11]
Vaccine against HIV virus; Anthrax vaccine (from tobacco) Antibodies against Ebola virus [9] By being able to genetically alter plants to create specific antibodies ...
Research initiated at ASU and funded by the US Army in 2002 focused on use of tobacco to bio-manufacture vaccines and monoclonal antibodies to prevent for treat disease caused by potential biological warfare agents. [16] [18] In 2011, he and his team at the Biodesign Institute were developing a vaccine for the Ebola virus using mice.
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The 2018 Équateur province Ebola outbreak occurred in the north-west of the Democratic Republic of the Congo (DRC) from May to July 2018. It was contained entirely within Équateur province, and was the first time that vaccination with the rVSV-ZEBOV Ebola vaccine had been attempted in the early stages of an Ebola outbreak, [6] with a total of 3,481 people vaccinated.
In April 2019, following a large-scale ring-vaccination scheme in the DRC outbreak, the WHO published the preliminary results of its research, in association with the DRC's Institut National pour la Recherche Biomedicale, into the effectiveness of the ring vaccination program, stating that the rVSV-ZEBOV-GP vaccine had been 97.5% effective at stopping Ebola transmission, relative to no ...