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  2. Total body irradiation - Wikipedia

    en.wikipedia.org/wiki/Total_body_irradiation

    Total body irradiation (TBI) is a form of radiotherapy used primarily as part of the preparative regimen for haematopoietic stem cell (or bone marrow) transplantation.As the name implies, TBI involves irradiation of the entire body, though in modern practice the lungs are often partially shielded to lower the risk of radiation-induced lung injury.

  3. Donor lymphocyte infusion - Wikipedia

    en.wikipedia.org/wiki/Donor_lymphocyte_infusion

    Formerly, the only treatment option that offered relapsed bone marrow transplant patients hope of a cure was another bone marrow transplant. However, the risk of serious, life-threatening complications after a second BMT is great. One strategy of managing relapse, donor leukocyte infusion, might eliminate the need for a second BMT in some patients.

  4. Hematopoietic stem cell transplantation - Wikipedia

    en.wikipedia.org/wiki/Hematopoietic_stem_cell...

    The first physician to perform a successful human bone-marrow transplant on a disease other than cancer was Robert A. Good at the University of Minnesota in 1968. [75] In 1975, John Kersey, also of the University of Minnesota, performed the first successful bone-marrow transplant to cure lymphoma.

  5. Stem-cell therapy - Wikipedia

    en.wikipedia.org/wiki/Stem-cell_therapy

    While it is thought that bone-marrow-derived stem cells are preferred for bone, cartilage, ligament, and tendon repair, others believe that the less challenging collection techniques and the multi-cellular microenvironment already present in adipose-derived stem cell fractions make the latter the preferred source for autologous transplantation ...

  6. Microtransplantation - Wikipedia

    en.wikipedia.org/wiki/Microtransplantation

    The cells employed are allogeneic peripheral blood stem cells. Matched HLA between donor and recipient is not necessary. The stem cells are collected from donor’s blood through a process known as apheresis after a certain period of daily subcutaneous injections of Granulocyte-colony stimulating factor, serving to mobilize stem cells from the donor's bone marrow into the peripheral circulation.

  7. Bone marrow - Wikipedia

    en.wikipedia.org/wiki/Bone_marrow

    A bone marrow harvest in progress The preferred sites for the procedure. In a bone marrow transplant, hematopoietic stem cells are removed from a person and infused into another person or into the same person at a later time . If the donor and recipient are compatible, these infused cells will then travel to the bone marrow and initiate blood ...

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