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Benzyl benzoate is an effective and inexpensive topical treatment for human scabies. [7] It has vasodilating and spasmolytic effects and is present in many asthma and whooping cough drugs. [ 8 ] It is also used as an excipient in some testosterone -replacement medications (like Nebido ) for treating hypogonadism .
Denatonium, usually available as denatonium benzoate (under trade names such as Denatrol, BITTERANT-b, BITTER+PLUS, Bitrex, Bitrix, and Aversion) and as denatonium saccharinate (BITTERANT-s), is the most bitter chemical compound known, with bitterness thresholds of 0.05 ppm for the benzoate and 0.01 ppm for the saccharinate. [1]
ɪ k /) is a white (or colorless) solid organic compound with the formula C 6 H 5 COOH, whose structure consists of a benzene ring (C 6 H 6) with a carboxyl (−C(=O)OH) substituent. The benzoyl group is often abbreviated "Bz" (not to be confused with "Bn," which is used for benzyl ), thus benzoic acid is also denoted as BzOH, since the benzoyl ...
In IUPAC nomenclature, the prefix benzyl refers to a C 6 H 5 CH 2 substituent, for example benzyl chloride or benzyl benzoate. Benzyl is not to be confused with phenyl with the formula C 6 H 5 . The term benzylic is used to describe the position of the first carbon bonded to a benzene or other aromatic ring.
Benzoyl chloride is a favored source of benzoyl groups, being used to prepare benzoyl ketones, benzamides (benzoyl amides), and benzoate esters. The source of many naturally occurring benzoyl compounds is the thioester benzoyl-CoA. Irradiation of benzil generates benzoyl radicals, which have the formula PhCO.
PRL-8-53 is relatively non-toxic, with an oral LD 50 in mice of 860 mg/kg, giving the drug a high therapeutic index.Doses above 8 mg/kg have brief hypotensive effects in canines.