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The gastric folds (or gastric rugae) are coiled sections of tissue that exist in the mucosal and submucosal layers of the stomach. [1] They provide elasticity by allowing the stomach to expand when a bolus enters it. These folds stretch outward through the action of mechanoreceptors, which respond to the increase in pressure. [2]
The muscular layer consists of two layers of muscle, the inner and outer layer. [3] The muscle of the inner layer is arranged in circular rings around the tract, whereas the muscle of the outer layer is arranged longitudinally. The stomach has an extra layer, an inner oblique muscular layer. [1]
The epithelial lining of the gland ducts is of the same character and is continuous with the general epithelial lining of the stomach. The sodium-iodide symporter (SIP) is expressed in all the surface mucous cells (at the basolateral membrane) but not in the mucous neck cells.
The inner part of the stomach wall is the gastric mucosa a mucous membrane that forms the lining of the stomach. the membrane consists of an outer layer of columnar epithelium, a lamina propria, and a thin layer of smooth muscle called the muscularis mucosa. Beneath the mucosa lies the submucosa, consisting of fibrous connective tissue. [19]
Rugae folds behind the anterior teeth in the hard palate of the mouth. In anatomy, rugae (sg.: ruga) are a series of ridges produced by folding of the wall of an organ. [1]In general, rugae are a biological feature found in many organisms, serving purposes such as increasing surface area, flexibility, or structural support.
The inner circular is helical with a steep pitch and the outer longitudinal is helical with a much shallower pitch. [24] Whilst the muscularis externa is similar throughout the entire gastrointestinal tract, an exception is the stomach which has an additional inner oblique muscular layer to aid with grinding and mixing of food.
The peritoneum is the serous membrane forming the lining of the abdominal cavity or coelom in amniotes and some invertebrates, such as annelids.It covers most of the intra-abdominal (or coelomic) organs, and is composed of a layer of mesothelium supported by a thin layer of connective tissue.
The mucus allows the acid at pH above 4 to penetrate lining, but below pH 4 (i.e. when acid is more concentrated) the acid cannot penetrate the mucus. This is called viscous fingering. [ 6 ] Thus the foveolar cells can pump out a lot of acid, but acid once in the lumen of the stomach is prevented from returning.
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