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Radical hydroxyl attacks can form baseless sites. Hydroxyl radicals can attack the deoxyribose DNA backbone and bases, potentially causing a plethora of lesions that can be cytotoxic or mutagenic. Cells have developed complex and efficient repair mechanisms to fix the lesions.
The name "tight binding" of this electronic band structure model suggests that this quantum mechanical model describes the properties of tightly bound electrons in solids. . The electrons in this model should be tightly bound to the atom to which they belong and they should have limited interaction with states and potentials on surrounding atoms of the sol
Nålebound socks from Egypt (300–500 AD) Mittens done in "nålebinding" Swedish nålebinding mittens, late 19th century. Nålebinding (Danish and Norwegian: literally 'binding with a needle' or 'needle-binding', also naalbinding, nålbinding, nålbindning, or naalebinding) is a fabric creation technique predating both knitting and crochet.
The APE1 enzyme creates a nick in the phosphodiester backbone at an abasic (baseless) site through a simple acyl substitution mechanism. First, the Asp210 residue in the active site deprotonates a water molecule, which can then perform a nucleophilic attack on the phosphate group located 5´ to the AP site.
Some of these COMINT reports were also published a few months previously in Nicholson Baker's book, Baseless. [54] One report from an identified Chinese military unit on February 26, 1952, said, "yesterday it was discovered that in our bivouac area there was a real flood of bacteria and germs from a plane by the enemy.
Foot binding (simplified Chinese: 缠足; traditional Chinese: 纏足; pinyin: chánzú), or footbinding, was the Chinese custom of breaking and tightly binding the feet of young girls to change their shape and size. Feet altered by foot binding were known as lotus feet and the shoes made for them were known as lotus shoes.