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Mepacrine, also called quinacrine or by the trade names Atabrine or Atebrin, is a medication with several uses. It is related to chloroquine and mefloquine . Although available from compounding pharmacies , as of August 2020 approved formulations are not available in the United States.
More severe side effects include deafness, low blood platelets, and an irregular heartbeat. [5] Use can make one more prone to sunburn. [5] While it is unclear if use during pregnancy carries potential for fetal harm, treating malaria during pregnancy with quinine when appropriate is still recommended. [5]
There is one study supporting the use of a novel combination of dextromethorphan and low dose quinidine in alleviating symptoms of easy laughing and crying (pseudobulbar affect); these are a type of rather severe uncontrollable behaviors which can be present in various neurological pathologies such as amyotrophic lateral sclerosis and multiple sclerosis.
The medicine is said to have no side effects due to its herbal composition and is based on the Unani concept of medicine. It's available across India in many medical and general shops. [2] Zinda Tilismath was made during the Nizams rule in Hyderabad, for which it acquired the Nizams crown (Dastaar) as its trade mark. The Marketing logo was the ...
Due to the risk of rare but serious side effects, it is not generally recommended to prevent malaria. [2] Though, the World Health Organization (WHO) in 2013 recommended use for seasonal preventive in children at high risk in combination with sulfadoxine and pyrimethamine. [4] Amodiaquine is a 4-aminoquinoline compound related to chloroquine. [2]
A 1964 report described the use of clioquinol in both the treatment and prevention of shigella infection and Entamoeba histolytica infection in institutionalized individuals at Sonoma State Hospital in California. The report indicates 4000 individuals were treated over a 4-year period with few side effects.
Tubocurarine (also known as d-tubocurarine or DTC) is a toxic benzylisoquinoline alkaloid historically known for its use as an arrow poison.In the mid-1900s, it was used in conjunction with an anesthetic to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Quipazine can produce tachycardia, including positive chronotropic and positive inotropic effects, through activation of the serotonin 5-HT 3 receptor. [ 2 ] Although quipazine does not generalize to dextroamphetamine in drug discrimination tests of dextroamphetamine-trained rodents, dextroamphetamine and cathinone have been found to partially ...