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BNP is synthesized as a 134-amino acid preprohormone (preproBNP), encoded by the human gene NPPB. Removal of the 26-residue N-terminal signal peptide generates the prohormone, proBNP, which is stored intracellularly as an O-linked glycoprotein; proBNP is subsequently cleaved between arginine-102 and serine-103 by a specific convertase (probably furin or corin) into NT-proBNP and the ...
The highest natural ground surface temperature ever recorded may have been an alleged reading of 93.9 °C (201.0 °F) at Furnace Creek, California, United States, on 15 July 1972. [7] In 2011, a ground temperature of 84 °C (183.2 °F) was recorded in Port Sudan , Sudan. [ 8 ]
BNP was first discovered in pig brain tissue but was later found more abundant in the heart (Mukoyama et al. 1991; Mukoyama et al. 1990). The human gene that encodes for BNP is called NPPB (GeneID 4879) and is located on chromosome 1 at 1p36.2. In mice, NPPb is found on chromosome 4. [3]
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For much of the past decade, policymakers and analysts have decried America's incredibly low savings rate, noting that U.S. households save a fraction of the money of the rest of the world.
Christopher Michael Langan (born March 25, 1952) is an American horse rancher and former bar bouncer, known for scoring highly on an IQ test that gained him entry to a high-IQ society and for being formerly listed in the Guinness Book of Records high IQ section under the pseudonym of Eric Hart, alongside Marilyn vos Savant and Keith Raniere.
The 4 Nations Face-Off championship between the USA and Canada on Thursday night drew a significant audience for ESPN's broadcast.. Canada's 3-2 victory over the USA in overtime averaged 9.3 ...
The current official highest registered air temperature on Earth is 56.7 °C (134.1 °F), recorded on 10 July 1913 at Furnace Creek Ranch, in Death Valley in the United States. [1] For few years, a former record that was measured in Libya had been in place, until it was decertified in 2012 based on evidence that it was an erroneous reading.