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Lamotrigine, sold under the brand name Lamictal among others, is a medication used to treat epilepsy and stabilize mood in bipolar disorder. [ 5 ] [ 8 ] For epilepsy, this includes focal seizures , tonic-clonic seizures , and seizures in Lennox-Gastaut syndrome . [ 8 ]
Valproate (valproic acid, VPA, sodium valproate, and valproate semisodium forms) are medications primarily used to treat epilepsy and bipolar disorder and prevent migraine headaches. [7] They are useful for the prevention of seizures in those with absence seizures , partial seizures , and generalized seizures . [ 7 ]
Among bipolar patients taking anticonvulsants, those on lamotrigine have a better cognitive profile than those on carbamazepine, valproate, topiramate, and zonisamide. [36] Although decreased verbal memory and slowed psychomotor speed are common side effects of lithium use [37] [38] these side effects usually disappear after discontinuation of ...
Lamotrigine (aka Lamictal) FDA approved for bipolar disorder maintenance therapy, not for acute mood problems like depression or mania/hypomania. [10] The usual target dose is 100–200 mg daily, titrated to by 25 mg increments every 2 weeks. [11] Lamotrigine can cause Stevens–Johnson syndrome, a very rare but potentially fatal skin condition ...
Adding small doses of lamotrigine to sodium valproate may be the best combination in resistant cases. Although ethosuximide is effective in treating only absence seizures, valproic acid is effective in treating multiple seizure types including tonic-clonic seizure and partial seizure , suggesting it is a better choice if a patient is exhibiting ...
According to guidelines by the American Academy of Neurology and American Epilepsy Society, [42] mainly based on a major article review in 2004, [43] patients with newly diagnosed epilepsy who require treatment can be initiated on standard anticonvulsants such as carbamazepine, phenytoin, valproic acid/valproate semisodium, phenobarbital, or on ...
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Lamotrigine (Lamictal) Oxcarbazepine; Topiramate; Valproic acid, sodium valproate, and valproate semisodium; Lithium pharmacology – lithium carbonate, lithium citrate, and lithium sulfate; Antipsychotics; Anxiety; Alprazolam (Solanax and Xanax) List of benzodiazepines