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Lymphadenopathy may be classified by: Size, where lymphadenopathy in adults is often defined as a short axis of one or more lymph nodes is greater than 10mm. [29] By extent: Localized lymphadenopathy: due to localized spot of infection; e.g., an infected spot on the scalp will cause lymph nodes in the neck on that same side to swell up
However, when two or more lymph node groups are involved, it is called generalized lymphadenopathy. Usually this is in response to significant systemic disease and will subside once the person has recovered. Sometimes it can persist long-term, even when no explanation for the lymphadenopathy can be found.
Generalized lymphadenopathy is swollen lymph glands in many areas of the body. [ 1 ] Usually this is in response to a body-wide infectious disease such as influenza and will go away once the person has recovered, but sometimes it can persist long-term, even when there is no obvious cause of disease.
The periaortic lymph node group is divided into three subgroups: preaortic, paraaortic, and retroaortic: The preaortic group drains the gastrointestinal viscera. They can be subdivided into three groups: the celiac nodes, the superior mesenteric nodes, and the inferior mesenteric nodes.
Virchow's nodes are named after Rudolf Virchow (1821–1902), the German pathologist who first described the nodes and their association with gastric cancer in 1848. [4] The French pathologist Charles Emile Troisier noted in 1889 that other abdominal cancers, too, could spread to the nodes.
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The jugulodigastric lymph nodes are found in the proximity of where the posterior belly of the digastric muscle crosses the internal jugular vein.Nodes are typically around 15 mm in length in adults, and decrease in size during old age. [1]
Löfgren syndrome includes some of the same symptoms as traditional sarcoidosis, and presents with erythema nodosum (especially of the lower extremities), bilateral arthritis of the ankle joints, and hilar lymphadenopathy. (Note: Other symptoms are classically not present in Löfgren syndrome.)