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  2. Hallmarks of aging - Wikipedia

    en.wikipedia.org/wiki/Hallmarks_of_aging

    Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. The hallmarks of aging are the types of biochemical changes that occur in all organisms that experience biological aging and lead to a progressive loss of physiological integrity, impaired function and, eventually, death.

  3. Arterial stiffness - Wikipedia

    en.wikipedia.org/wiki/Arterial_stiffness

    Degenerative changes that occur with age in the walls of large elastic arteries are thought to contribute to increased stiffening over time, including the disruption of lamellar elastin structures within the wall, possibly due to repeated cycles of mechanical stress; inflammation; [7] changes in arterial collagen proteins, partially as a ...

  4. Senescence - Wikipedia

    en.wikipedia.org/wiki/Senescence

    Senescence (/ s ɪ ˈ n ɛ s ə n s /) or biological aging is the gradual deterioration of functional characteristics in living organisms. Whole organism senescence involves an increase in death rates or a decrease in fecundity with increasing age, at least in the later part of an organism's life cycle.

  5. Biomarkers of aging - Wikipedia

    en.wikipedia.org/wiki/Biomarkers_of_aging

    The uses for biomarkers of aging are ubiquitous and identifying a physical parameter of biological aging would allow humans to determine our true age, mortality, and morbidity. [10] The change in the physical biomarker should be proportional to the change in the age of the species.

  6. Aging-associated diseases - Wikipedia

    en.wikipedia.org/wiki/Aging-associated_diseases

    An aging-associated disease (commonly termed age-related disease, ARD) is a disease that is most often seen with increasing frequency with increasing senescence. They are essentially complications of senescence, distinguished from the aging process itself because all adult animals age ( with rare exceptions ) but not all adult animals ...

  7. Ageing - Wikipedia

    en.wikipedia.org/wiki/Ageing

    In the field of sociology and mental health, ageing is seen in five different views: ageing as maturity, ageing as decline, ageing as a life-cycle event, ageing as generation, and ageing as survival. [126] Positive correlates with ageing often include economics, employment, marriage, children, education, and sense of control, as well as many ...

  8. Atherosclerosis - Wikipedia

    en.wikipedia.org/wiki/Atherosclerosis

    This study showed that heart disease could affect people at a younger age and was not just a problem for older individuals. [ 118 ] [ 119 ] [ 120 ] In 1992, a report showed that microscopic fatty streaks were seen in the left anterior descending artery in over 50% of children aged 10–14 and 8% had even more advanced lesions with more ...

  9. Clinical death - Wikipedia

    en.wikipedia.org/wiki/Clinical_death

    With the advent of these strategies, cardiac arrest came to be called clinical death rather than simply death, to reflect the possibility of post-arrest resuscitation. At the onset of clinical death, consciousness is lost within several seconds, and in dogs, measurable brain activity has been measured to stop within 20 to 40 seconds. [ 2 ]