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It occurs equally between men and women with a male to female ratio of 1.2:1. Mean onset age is 27, but has been seen in people aged 16 to 40. [1] It is known to occur after or concurrently with a systemic infection (but not always), showing that it is related generally to an altered immune system. Recurrent episodes can happen, but are ...
Symptoms include blurred vision in both eyes, but the onset may occur at a different time in each eye. There are yellow-white placoid lesions in the posterior pole at the level of the retinal pigment epithelium. Some suggest a genetic predisposition to the disease, while others postulate an abnormal immune response to a virus. [2]
Hollenhorst plaques may cause retinal occlusion, where the plaque blocks blood flow through the retinal vessels, resulting in temporary or permanent vision loss in the affected eye. [1] However, while Hollenhorst plaques do become lodged in retinal arteries, they generally do not fully prevent blood flow so do not cause ischemia. [1] Once a ...
Cotton wool spots are also associated with giant cell arteritis (GCA), a type of inflammation of the lining of the arteries, as this may reduce blood flow to the eyes. [1] In a study of 123 subjects with vision loss due to early stage giant cell arteritis, one-third of subjects had cotton wool spots present in their eyes. [2]
Palpebral form- Usually upper tarsal conjunctiva of both the eyes is involved. Typical lesion is characterized by the presence of hard, flat-topped papillae arranged in cobblestone or pavement stone fashion. In severe cases papillae undergo hypertrophy to produce cauliflower-like excrescences of 'giant papillae'.
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Episcleritis of a 40 year old female. Symptoms of episcleritis typically include painless redness of the eye (mild pain is possible but atypical), and watery eyes. [2] The pain of episcleritis is typically mild, less severe than in scleritis, [3] and may be tender to palpation.
The membrane does not normally detach from the vitreous base, although it can be detached with extreme trauma. However, the vitreous base may have an irregular posterior edge. When the edge is irregular, the forces of the vitreous membrane peeling off the retina can become concentrated at small posterior extensions of the vitreous base.