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Cyanosis is the change of body tissue color to a bluish-purple hue, as a result of decrease in the amount of oxygen bound to the hemoglobin in the red blood cells of the capillary bed. [1] Cyanosis is apparent usually in the body tissues covered with thin skin, including the mucous membranes, lips, nail beds, and ear lobes. [1]
In addition to cyanosis, they often show signs of tachypnea (fast breathing), a heart murmur, and decreased peripheral pulses. [ 6 ] [ 31 ] If congenital heart disease is suspected in a newborn, doctors will likely perform several tests to evaluate the heart, including a chest x-ray , echocardiogram , and electrocardiogram . [ 32 ]
Acrocyanosis may be a sign of a more serious medical problem, such as connective tissue diseases and diseases associated with central cyanosis. Other causative conditions include infections, toxicities, antiphospholipid syndrome, cryoglobulinemia, neoplasms. In these cases, the observed cutaneous changes are known as "secondary acrocyanosis".
Traumatic asphyxia is characterized by cyanosis in the upper extremities, neck, and head as well as petechiae in the conjunctiva. Patients can also display jugular venous distention and facial edema. [3] Associated injuries include pulmonary contusion, myocardial contusion, hemo/pneumothorax, and broken ribs. [4] [5]
Early cyanosis is a symptom of a right-to-left shunt. [2] A right-to-left shunt results in decreased blood flow through the pulmonary system, leading to decreased blood oxygen levels ( hypoxemia ). Hypoxemia manifests as cyanosis, causing "blue babies."
Cyanosis, indicates deficiency of oxygen in the blood, is a late sign of extremely severe pulmonary edema. [ 31 ] Other signs of left ventricular failure include a laterally displaced apex beat (which occurs when the heart is enlarged) and a gallop rhythm (additional heart sounds), which may be heard as a sign of increased blood flow or ...
An overdose can cause stupor, changes in pupil size, clammy skin, cyanosis, coma and respiratory failure leading to death. What is fentanyl? A look at the drug at the center of a recent major ...
Cyanosis is the most common sign of hemoglobin M disease, which can be observed in all kinds of hemoglobin M diseases. It is mostly presented in the patient's lips and fingertips. [15] Cyanosis in hemoglobin M disease results from elevated levels of metHb and sulfhemoglobin (sulfHb). [16] Dark brown blood is another major sign of hemoglobin M ...