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Using PREVENT to calculate the 10-year risk for developing heart disease, the researchers determined that some 40% fewer people would have met the criteria for a statin prescription.
Researchers tested simvastatin, later sold by Merck as Zocor, on 4,444 patients with high cholesterol and heart disease. After five years, the study concluded the patients saw a 35% reduction in their cholesterol, and their chances of dying of a heart attack were reduced by 42%. [12] [191] In 1995, Zocor and Mevacor both made Merck over US$1 ...
When examining the cost-effectiveness of statin use in older adults, the researchers report that statins were cost-effective, with the cost per quality-adjusted life years gained below £3,502 ...
A 2010 meta-analysis demonstrated that every 255 people treated with a statin for four years produced a reduction of 5.4 major coronary events and induced only one new case of diabetes. [62] In some case and clinical studies mild muscle pain or weakness have been reported (around 3%), compared to a placebo.
A risk exists of muscle damage (myopathy and rhabdomyolysis) with statins. Hypercholesterolemia is not a risk factor for mortality in persons older than 70 years and risks from statin drugs are more increased after age 85. [2] Fibrates are indicated for hypertriglyceridemia. Fibrates typically lower triglycerides by 20% to 50%.
However, taking steps to support your heart health can help you lower your risk of many types of cardiovascular disease, such as stroke or heart attacks. This article originally appeared on Hims ...
A United States guideline recommends statins in those who have a 12% or greater risk of cardiovascular disease over the next ten years. [166] Niacin , fibrates and CETP Inhibitors , while they may increase HDL cholesterol do not affect the risk of cardiovascular disease in those who are already on statins. [ 167 ]
But chatbots can help you navigate your way to better health—if you know how to harness the power and avoid the pitfalls, says Isaac “Zak” Kohane M.D., Ph.D., of Harvard Medical School.