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The incidence of liver damage from herbal and dietary supplements is about 16–20% of all supplement products causing injury, with the occurrence growing globally over the early 21st century. [2] The most common liver injuries from weight loss and bodybuilding supplements involve hepatocellular damage and jaundice.
The best approach to specifically achieve muscle growth remains controversial (as opposed to focusing on gaining strength, power, or endurance); it was generally considered that consistent anaerobic strength training will produce hypertrophy over the long term, in addition to its effects on muscular strength and endurance.
Supplements are taken to increase endurance, energy, and focus during a workout. [1] Pre-workout supplements contain a variety of ingredients such as caffeine and creatine, differing by capsule or powder products. [2] [3] The first pre-workout product entered the market in 1982, and since then the category has grown in use. [4]
β-Hydroxy β-methylbutyric acid [note 1] (HMB), otherwise known as its conjugate base, β-hydroxy β-methylbutyrate, is a naturally produced substance in humans that is used as a dietary supplement and as an ingredient in certain medical foods that are intended to promote wound healing and provide nutritional support for people with muscle wasting due to cancer or HIV/AIDS.
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