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They worked primarily by suppressing appetite, and had other beneficial effects such as increased alertness. Use of amphetamines increased over the subsequent decades, including Obetrol and culminating in the "rainbow diet pill" regime. [38] This was a combination of multiple pills, all thought to help with weight loss, taken throughout the day.
Phentermine is an norepinephrine and dopamine releasing agent (NDRA) and produces stimulant, rewarding, and appetite suppressant effects. [8] [9] [10] Chemically, it is a substituted amphetamine. [11] Phentermine was approved for medical use in the United States in 1959. [3] It is available as a generic medication. [3]
Phentermine is a stimulant and appetite suppressant. [3] Topiramate is an anticonvulsant that has weight loss side effects. [ 3 ] The exact mechanism of action for both drugs is unknown.
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