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3D medical illustration depicting the TNM stages in breast cancer. Cancer staging can be divided into a clinical stage and a pathologic stage. In the TNM (Tumor, Node, Metastasis) system, clinical stage and pathologic stage are denoted by a small "c" or "p" before the stage (e.g., cT3N1M0 or pT2N0).
In hematology, plasma cell dyscrasias (also termed plasma cell disorders and plasma cell proliferative diseases) are a spectrum of progressively more severe monoclonal gammopathies in which a clone or multiple clones of pre-malignant or malignant plasma cells (sometimes in association with lymphoplasmacytoid cells or B lymphocytes) over-produce and secrete into the blood stream a myeloma ...
One example is an enzyme called tyrosinase that, when expressed at high levels, transforms certain skin cells (for example, melanocytes) into tumors called melanomas. [ 137 ] [ 138 ] A third possible source of tumor antigens are proteins normally important for regulating cell growth and survival, that commonly mutate into cancer inducing ...
Although 70–90 percent of people with appendicitis may have an elevated white blood cell (WBC) count, many other abdominal and pelvic conditions can cause the WBC count to be elevated. [48] However, a high WBC count may not alone represent a solid indicator of appendicitis but rather an inflammation [15] but the neutrophil ratio was more ...
Commercially available urine antigen testing appears to be quite sensitive in suggesting the diagnosis in cases where the organism is not readily detected. [26] However, commercial antigen tests have a high degree of cross-reactivity with other endemic fungal conditions such as histoplasmosis , and thus cannot distinguish blastomycosis from ...
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