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The theory behind contrast bath therapy is that the hot water causes vasodilation of the blood flow in the limb or body followed by the cold water which causes vasoconstriction. [1] The lymph system , unlike the circulatory system, lacks a central pump.
Alpha 1 blockers inhibit vasoconstriction normally initiated by the baroreceptor reflex upon postural change and the subsequent drop in pressure. [26] Other antihypertensive medications may also cause orthostatic hypotension, in addition to anticholinergics , dopaminergic drugs, opiates and psychoactive medications .
The hunting reaction or hunting response is a process of alternating vasoconstriction and vasodilation in extremities exposed to cold. The term Lewis reaction is used too, named after Thomas Lewis, who first described the effect in 1930. [1] Vasoconstriction occurs first to reduce heat loss, but also results in strong cooling of the extremities.
Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles. The process is the opposite of vasodilation , the widening of blood vessels.
The ability of baroreflex activation therapy to reduce sympathetic nerve activity suggests a potential in the treatment of chronic heart failure, because in this condition there is often intense sympathetic activation and patients with such sympathetic activation show a markedly increased risk of fatal arrhythmias and death. [citation needed]
Vascular resistance is the resistance that must be overcome for blood to flow through the circulatory system.The resistance offered by the systemic circulation is known as the systemic vascular resistance or may sometimes be called by another term total peripheral resistance, while the resistance caused by the pulmonary circulation is known as the pulmonary vascular resistance.
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Single strand is the most efficient form of RNA for the facilitation of transcription and translation. This will help to counteract the decreased efficiency of transcription and translation brought about by the cold shock. [9] Cold shock proteins also affect the formation of hairpin structures in the RNA, blocking them from being formed.