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The spinothalamic tract is a nerve tract in the anterolateral system in the spinal cord. [1] This tract is an ascending sensory pathway to the thalamus.From the ventral posterolateral nucleus in the thalamus, sensory information is relayed upward to the somatosensory cortex of the postcentral gyrus.
The spinohypothalamic tract or spinohypothalamic fibers is a sensory fiber tract projecting from the spinal cord to the hypothalamus directly to mediate reflex autonomic and endocrine responses to painful stimuli (the hypothalamus receives additional indirect nociceptive projections from the reticular formation (see: spinoreticular tract), and periaqueductal gray (see: spinomesencephalic tract).
The substantia gelatinosa is one point (the nucleus proprius being the other) where first order neurons of the spinothalamic tract synapse. Many μ and κ-opioid receptors , presynaptic and postsynaptic , are found on these nerve cells; they can be targeted to manage pain of distal origin.
Spinothalamic tract (STT) cells that project from laminae I and V in the lumbosacral area of the spinal cord project to the VPL in the VB. [2] STT cells located in the cervical area of the spinal cord are the densest and project from the neck of the dorsal horn to the VPL of the VB. Most projections to the VB are contralateral while only a few ...
The spinothalamic tract is a sensory pathway originating in the spinal cord. It transmits information to the thalamus about pain, temperature, itch and crude touch . There are two main parts: the lateral spinothalamic tract , which transmits pain and temperature, and the anterior (or ventral) spinothalamic tract , which transmits crude touch ...
The ascending pain and temperature fibers of the spinothalamic tract send information to the PAG via the spinomesencephalic pathway (so-named because the fibers originate in the spine and terminate in the PAG, in the mesencephalon or midbrain). This region has been used as the target for brain-stimulating implants in patients with chronic pain.
The dorsal column–medial lemniscus pathway (DCML) (also known as the posterior column-medial lemniscus pathway (PCML) is the major sensory pathway of the central nervous system that conveys sensations of fine touch, vibration, two-point discrimination, and proprioception (body position) from the skin and joints.
This emanates from larger pyramidal cells and is much thicker. Its ending is small, dense and globular. Its synapses are located close to the soma of the thalamic neuron, often forming the center of glomerular complexes. The isothalamus serves the function of transforming and distributing "prethalamic" information to the cortex.