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Frequency. 1 per 1000 people [8] Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [5] Those affected often have a gradual onset. [5] The most common initial symptoms are feeling tired and weak. [4]
Owing to the extremely efficient enterohepatic circulation of B 12, the liver can store 3 to 5 years' worth of vitamin B 12; therefore, nutritional deficiency of this vitamin is rare in adults in the absence of malabsorption disorders. [12] In the absence of intrinsic factor or distal ileum receptors, only months to a year of vitamin B 12 are ...
6% (< 60 years old), 20% (> 60 years old) [4] Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [5] Symptoms can vary from none to severe. [1] Mild deficiency may have few or absent symptoms. [1]
Over time, a deficiency of B12 can cause problems with balance, confusion, depression, poor memory and possibly dementia, and it can even cause permanent damage to the nervous system, Somers says.
Fortunately, though, vitamin B12 isn't so hard to get enough of because it's so widely dispersed in the food supply and daily needs are relatively low. 4 Overlooked Causes of Vitamin B12 ...
Autoimmune hepatitis, formerly known as lupoid hepatitis, plasma cell hepatitis, or autoimmune chronic active hepatitis, is a chronic, autoimmune disease of the liver that occurs when the body's immune system attacks liver cells, causing the liver to be inflamed. Common initial symptoms may include fatigue, nausea, muscle aches, or weight loss ...