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In humans, the presence of the Y chromosome is responsible for triggering male development; in the absence of the Y chromosome, the fetus will undergo female development, except with various exceptions such as individuals with Swyer syndrome, that have XY chromosomes and a female phenotype, and de la Chapelle Syndrome, that have XX chromosomes ...
Most mammals, including humans, have an XY sex-determination system: the Y chromosome carries factors responsible for triggering male development. In the absence of a Y chromosome, the fetus will undergo female development. This is because of the presence of the sex-determining region of the Y chromosome, also known as the SRY gene. [5]
Two use homomorphic male heterogamety, one uses XX/XY, one uses ZZ/ZW. Remarkably, the X and Z chromosomes are homologous, and the Y and W as well. Dmrt1 is on autosome 1 and not sex-linked. This means that an XX female individual is genetically similar to a ZZ male individual, and an XY male individual is to a ZW female individual.
XX male syndrome, also known as de la Chapelle syndrome, is a rare intersex condition in which an individual with a 46,XX karyotype develops a male phenotype. [2] Synonyms for XX male syndrome include 46,XX testicular difference of sex development (or 46,XX DSD) [3] [4] [5] [6]
The sex chromosome in a human egg is always an X chromosome since a female only has X sex chromosomes. In sperm, about half the sperm have an X chromosome and half have a Y chromosome. [2] If an egg fuses with sperm with a Y chromosome, the resulting individual is male.
Two of the 46 chromosomes, known as X and Y, are called sex chromosomes because they help determine whether a person will develop male or female sex characteristics. Females typically have two X chromosomes (46,XX), and males have one X chromosome and one Y chromosome (46,XY). 48,XXYY syndrome results from the presence of an extra copy of both ...
Male sterility likely arises first as an adaptation to prevent selfing. Once male sterility has reached a certain prevalence, then female sterility may have a chance to arise and spread. [13] In the domesticated papaya (Carica papaya), three sex chromosomes are present, denoted as X, Y and Y h. This corresponds with three sexes: females with XX ...
Sexual differentiation is the process of development of the sex differences between males and females from an undifferentiated zygote. [1] [2] Sex determination is often distinct from sex differentiation; sex determination is the designation for the development stage towards either male or female, while sex differentiation is the pathway towards the development of the phenotype.