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Acoustic neuroma - a slow-growing, benign tumor of the acoustic nerve. [2] Symptoms, which most often start after the age of 30, can include dizziness, headache, vertigo, loss of balance, ringing sensations, and numbness. [3] Ganglioneuroma - a tumor of the sympathetic nerve fibers arising from neural crest cells. [4]
Pacinian corpuscles are rapidly adapting phasic receptors that detect gross pressure changes and vibrations in the skin. [6] Pacinian corpuscles have a large receptive field on the skin's surface with an especially sensitive center. [7] The corpuscles are especially sensitive to vibrations, which they can sense even centimeters away. [7]
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Cutaneous receptors are at the ends of afferent neurons. works within the capsule. Ion channels are situated near these networks. In sensory transduction, the afferent nerves transmit through a series of synapses in the central nervous system, first in the spinal cord, the ventrobasal portion of the thalamus, and then on to the somatosensory cortex.
Pallesthesia (\ˌpal-es-ˈthē-zh(ē-)ə\), or vibratory sensation, is the ability to perceive vibration. [1] [2] This sensation, often conducted through skin and bone, is usually generated by mechanoreceptors such as Pacinian corpuscles, Merkel disk receptors, and tactile corpuscles. [1]
Symptoms may include: Swelling in the extremities (arms or legs), also called peripheral edema; the swelling often is painless. Difficulty in moving the extremity that has the tumor, including a limp. Soreness localized to the area of the tumor or in the extremity. Neurological symptoms. [3] Pain or discomfort: numbness, burning, or "pins and ...
Mulder's sign is a physical exam finding associated with Morton's neuroma, which may be elicited while the patient is in the supine position on the examination table. The pain of the neuroma, as well as a click, can be produced by squeezing the two metatarsal heads together with one hand, while concomitantly putting pressure on the interdigital space with the other hand.
Complex regional pain syndrome (CRPS Type 1 and Type 2), sometimes referred to by the hyponyms Reflex Sympathetic Dystrophy (RSD) or Reflex Neurovascular Dystrophy (RND), is a rare and severe form of neuroinflammatory and dysautonomic disorder causing chronic pain, neurovascular, and neuropathic symptoms.