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Decidualization is a process that results in significant changes to cells of the endometrium in preparation for, and during, pregnancy. This includes morphological and functional changes (the decidual reaction) to endometrial stromal cells (ESCs), the presence of decidual white blood cells (leukocytes), and vascular changes to maternal arteries.
The decidua is the modified mucosal lining of the uterus (that is, modified endometrium) that forms every month, in preparation for pregnancy. It is shed off each month when there is no fertilized egg to support. [1] The decidua is under the influence of progesterone. Endometrial cells become highly characteristic.
Before the fertilized ovum reaches the uterus, the mucous membrane of the body of the uterus undergoes important changes and is then known as the decidua.The thickness and vascularity of the mucous membrane are greatly increased; its glands are elongated and open on its free surface by funnel-shaped orifices, while their deeper portions are tortuous and dilated into irregular spaces.
The uterine glands, on the other hand, decrease in activity and degenerate around 8 to 9 days [30] after ovulation in absence of pregnancy. The decidual cells originate from the stromal cells that are always present in the endometrium, and make up a new layer, the decidua .
The endometrium is the inner epithelial layer, ... During pregnancy, ... which is termed endometrial transformation or decidualization. ...
The odds of a quintuplet pregnancy are 1 in over 50 million. Even with IUI, the odds of quintuplets are still exceedingly rare, since five mature follicles would (in theory) have been seen prior ...
Women's endometrium contains relaxin, which is an essential component that helps prepare the body for early pregnancy. [21] The endometrium is transformed into decidua during the early pregnancy maintenance procedure. [21] The process known as decidualization occurs when the endometrium changes both physiologically and morphologically in order ...
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