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  2. Tenosynovial giant cell tumor - Wikipedia

    en.wikipedia.org/wiki/Tenosynovial_giant_cell_tumor

    Tenosynovial giant cell tumor (TGCT) is a non-malignant tumor defined histologically as inclusions of “osteoclast-like” multinucleated giant cells, hemosiderin, and macrophages. [1] This histology can present one of 2 clinically distinct ways. TGCT tumors often develop from the lining of joints (also known as synovial tissue).

  3. Giant-cell tumor of bone - Wikipedia

    en.wikipedia.org/wiki/Giant-cell_tumor_of_bone

    Malignancy in giant-cell tumor is uncommon and occurs in about 2% of all cases. However, if malignant degeneration does occur, it is likely to metastasize to the lungs. Giant-cell tumors are normally benign, [1] with unpredictable behavior. [2] It is a heterogeneous tumor composed of three different cell populations.

  4. Non-ossifying fibroma - Wikipedia

    en.wikipedia.org/wiki/Non-ossifying_fibroma

    A non-ossifying fibroma (NOF) is a benign bone tumor of the osteoclastic, giant cell-rich tumor type. [1] It generally occurs in the metaphysis of long bones in children and adolescents. [2] Typically, there are no symptoms unless there is a fracture. [2]

  5. Giant cell - Wikipedia

    en.wikipedia.org/wiki/Giant_cell

    A giant cell (also known as a multinucleated giant cell, or multinucleate giant cell) is a mass formed by the union of several distinct cells (usually histiocytes), often forming a granuloma. [ 1 ] Although there is typically a focus on the pathological aspects of multinucleate giant cells (MGCs), they also play many important physiological roles.

  6. Chondroblastoma - Wikipedia

    en.wikipedia.org/wiki/Chondroblastoma

    Chondroblastoma is a rare, benign, locally aggressive bone tumor that typically affects the epiphyses or apophyses of long bones. [ 1 ] [ 2 ] It is thought to arise from an outgrowth of immature cartilage cells ( chondroblasts ) from secondary ossification centers , originating from the epiphyseal plate or some remnant of it.

  7. Giant-cell fibroblastoma - Wikipedia

    en.wikipedia.org/wiki/Giant-cell_fibroblastoma

    Giant cell fibroblastoma (GCF) is a rare type of soft-tissue tumor marked by painless nodules in the dermis (the inner layer of the two main layers of tissue that make up the skin) and subcutaneous (beneath the skin) tissue. These tumors may come back after surgery, but they do not spread to other parts of

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