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RNA folding problem: Is it possible to accurately predict the secondary, tertiary and quaternary structure of a polyribonucleic acid sequence based on its sequence and environment? Protein design : Is it possible to design highly active enzymes de novo for any desired reaction?
In economics and law, fungibility is the property of a good or a commodity whose individual units are essentially interchangeable. [1] [2] In legal terms, this affects how legal rights (such as ownership and the right to receive goods under a contract) apply to such items. Fungible things can be substituted for each other; for example, a $100 ...
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You are free: to share – to copy, distribute and transmit the work; to remix – to adapt the work; Under the following conditions: attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made.
You are free: to share – to copy, distribute and transmit the work; to remix – to adapt the work; Under the following conditions: attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made.
Dry media reactions have been developed in the wake of developments in microwave chemistry, and are a part of green chemistry. [2] The drive for the development of dry media reactions in chemistry is: economics (save money on solvents) ease of purification (no solvent removal post-synthesis) high reaction rate (due to high concentration of ...
One problem addressed by mixed cuprates is the economical use of the alkyl group. Thus, in some applications, the mixed cuprate with the formula Li 2 [Cu(2-thienyl)(CN)R] is prepared by combining thienyllithium and cuprous cyanide followed by the organic group to be transferred. In this higher order mixed cuprate, both the cyanide and thienyl ...
Ring opening as a means of ring expansion can also be applied to larger systems to give access to even larger ring syscyclization. The Grob fragmentation can be applied as an example of such an expansion. Like the pinacol type migration the Grob fragmentation relies on an electron donating group to promote the bond migration and encourage the ...