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The study was a "double-blind, placebo-controlled, randomized", 24-week trial running "from July 3, 2008, through October 5, 2009" with "250 patients with opioid dependence disorder" at "13 clinical sites in Russia" on the use of injectable naltrexone (XR-NTX) for opioid dependence.
Naltrexone (referred to as the “Ozempic of alcohol”) is a drug that can help reduce alcohol and opioid cravings for people living with substance misuse disorder. vitapix/Getty Images
The treatment is claimed by the C Three Foundation to have a 78% success rate in remedying alcohol dependence. [ 2 ] [ 5 ] : p. 293 Naltrexone is FDA approved for use in the United States. In 2013/4 the Scottish Medicines Consortium (SMC) approved nalmefene for use as part of the NHS National Services Scotland. [ 2 ]
Naltrexone is a long-acting opioid antagonist with few side effects. It is usually prescribed in outpatient medical conditions. Naltrexone blocks the euphoric effects of alcohol and opiates. Naltrexone cuts relapse risk in the first three months by about 36%. [22]
“For patients and the public, it means that medications primarily used for diabetes and weight loss could also help reduce alcohol dependence, addressing two major health issues concurrently ...
While all subjects received alcohol addiction counseling, compared to the group that received placebo medication, the naltrexone-treated subjects reported significantly reduced alcohol craving and less high or euphoria associated with drinking alcohol on occasions when they drank alcohol.
Naltrexone, an opioid receptor antagonist, is frequently prescribed to patients suffering from alcohol use disorder, with moderate effectiveness. [20] Studies have demonstrated that naltrexone reduces the stimulating and heightens the aversive sedative effects of alcohol in individuals at-risk for alcohol use disorder, contributing to decreases ...
Multiple studies have shown that low-dose naltrexone has promise as a treatment for chronic pain, some autoimmune disorders and cancers. [7] [8] [9] As of 2014, no peer-reviewed studies supporting low-dose naltrexone for multiple sclerosis (MS) have been published. [10] [11] Clinical trials for treatment of fibromyalgia were initiated in 2021. [12]
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