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Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage).
Controlled or modified-release formulations alter the rate and timing at which a drug is liberated, in order to produce adequate or sustained drug concentrations. [28] The first controlled-release (CR) formulation that was developed was Dexedrine in the 1950s. [ 13 ]
Modern methods of construction (MMC) is a term used mainly in the UK construction industry to refer to "smart construction" processes designed to improve upon traditional design and construction approaches by focusing on (among other things) component and process standardisation, design for manufacture and assembly (), prefabrication, preassembly, off-site manufacture (including modular ...
Release (Liberation) is the first step in the process by which medication enters the body and liberates the active ingredient that has been administered. The pharmaceutical drug must separate from the vehicle or the excipient that it was mixed with during manufacture. Some authors split the process of liberation into three steps: disintegration ...
Design–build (or design/build, and abbreviated D–B or D/B accordingly), also known as alternative delivery, [1] is a project delivery system used in the construction industry. It is a method to deliver a project in which the design and construction services are contracted by a single entity known as the design–builder or design–build ...
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The rebuilt upper reservoir of the Taum Sauk plant, nearing completion in this photo, is the largest RCC dam in North America. [1]Roller-compacted concrete (RCC) or rolled concrete (rollcrete) is a special blend of concrete that has essentially the same ingredients as conventional concrete but in different ratios, and increasingly with partial substitution of fly ash for portland cement. [2]
It is especially suited to the construction and rehabilitation of manholes due to their ability to withstand toxic and corrosive sewer gases and bacteria commonly found in sewer systems. Unlike traditional concrete structures, polymer concrete requires no coating or welding of PVC-protected seams. [ 4 ]