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  2. Hepatitis C - Wikipedia

    en.wikipedia.org/wiki/Hepatitis_C

    290,000 (2019) [4] Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; [2] it is a type of viral hepatitis. [6] During the initial infection period, people often have mild or no symptoms. [1] Early symptoms can include fever, dark urine, abdominal pain, and yellow tinged skin. [1]

  3. Sofosbuvir/velpatasvir - Wikipedia

    en.wikipedia.org/wiki/Sofosbuvir/velpatasvir

    Sofosbuvir/velpatasvir, sold under the brand name Epclusa among others, is a fixed-dose combination medication for the treatment of hepatitis C in adults. [2][5][6][7] It combines sofosbuvir and velpatasvir. [2][5][6] It is more than 90% effective for hepatitis C genotypes one through six. [2] It also works for hepatitis C in those who also ...

  4. Telaprevir - Wikipedia

    en.wikipedia.org/wiki/Telaprevir

    Telaprevir (VX-950), marketed under the brand names Incivek and Incivo, is a pharmaceutical drug for the treatment of hepatitis C co-developed by Vertex Pharmaceuticals and Johnson & Johnson. It is a member of a class of antiviral drugs known as protease inhibitors. [3] Specifically, telaprevir inhibits the hepatitis C viral enzyme NS3/4A ...

  5. Elbasvir/grazoprevir - Wikipedia

    en.wikipedia.org/wiki/Elbasvir/grazoprevir

    KEGG. D10778. Elbasvir/grazoprevir, sold under the brand name Zepatier, is a fixed-dose combination for the treatment of hepatitis C, containing elbasvir (an inhibitor of hepatitis C virus 's NS5A protein) and grazoprevir (an NS3 / 4A inhibitor). It is used to treat chronic hepatitis C virus (HCV) genotypes 1 or 4 infection in both treatment ...

  6. Sofosbuvir - Wikipedia

    en.wikipedia.org/wiki/Sofosbuvir

    Sofosbuvir is a prodrug of the Protide type, whereby the active phosphorylated nucleotide is granted cell permeability and oral bioavailability. It is metabolized to the active antiviral agent GS-461203 (2'-deoxy-2'-α-fluoro-β- C -methyluridine-5'-triphosphate).

  7. Hepatitis C virus - Wikipedia

    en.wikipedia.org/wiki/Hepatitis_C_virus

    The hepatitis C virus (HCV) [3] is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer (hepatocellular carcinoma, abbreviated HCC) and lymphomas in humans. [4][5]

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