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An oncovirus or oncogenic virus is a virus that can cause cancer. [4] This term originated from studies of acutely transforming retroviruses in the 1950–60s, [ 5 ] when the term oncornaviruses was used to denote their RNA virus origin. [ 6 ]
The Epstein–Barr virus (EBV) is one of the nine known human herpesvirus types in the herpes family, and is one of the most common viruses in humans. EBV is a double-stranded DNA virus and is also called human herpesvirus 4 (HHV-4). [2] Epstein–Barr virus (EBV) is the first identified oncogenic virus, or a virus that can cause cancer. EBV ...
An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by oncolysis , they release new infectious virus particles or virions to help destroy the remaining tumour.
Hepatitis virus-associated hepatocarcinogenesis is a serious health concern. [31] Liver cancer in the United States is primarily due to three main factors: hepatitis C virus (HCV) (22%), hepatitis B virus (HBV) (12%) and alcohol use (47%). [32] In 2017 there will be about 40,710 new cases of liver cancer in the United States. [33]
The discovery of specific small-molecule inhibitors that specifically target the different oncogenic proteins and a comprehensive mechanistic analysis of the ways in which oncogenes dysregulate physiological signaling to cause different cancer types and developmental syndromes are potential future advances in the field of cancer research.
The various lineages and sublineages have different oncogenic capacity, where overall, the non-European lineages are considered to increase the risk for cancer. [116] Although HPV16 is a DNA virus, there are signs of recombination among the different lineages.
Rous sarcoma virus (RSV) (/ r aʊ s /) is a retrovirus and is the first oncovirus to have been described. It causes sarcoma in chickens. As with all retroviruses, it reverse transcribes its RNA genome into cDNA before integration into the host DNA.
Oncology is a branch of medicine that deals with the study, treatment, diagnosis, and prevention of cancer.A medical professional who practices oncology is an oncologist. [1]