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Trazodone is associated with an increased risk of falls in older adults. [28] ... The elimination half-life of extended-release trazodone is 9.1 to 13.2 ...
Chemical structure of the serotonin antagonist and reuptake inhibitor trazodone.. Serotonin antagonist and reuptake inhibitors (SARIs) are a class of drugs used mainly as antidepressants, but also as anxiolytics and hypnotics.
This is a list of adverse effects of the antidepressant trazodone, sorted by frequency of occurrence. [1] [2] [3] Very common.
Improved reaction times were noted at 52 weeks in elderly patients free from benzodiazepines. This is an important function in the elderly, especially if they drive a car due to the increased risk of road traffic accidents in benzodiazepine users. [136] At the 24-week follow-up, 80% of people had successfully withdrawn from benzodiazepines.
Pindolol, sold under the brand name Visken among others, is a nonselective beta blocker which is used in the treatment of hypertension. [1] [2] It is also an antagonist of the serotonin 5-HT 1A receptor, preferentially blocking inhibitory 5-HT 1A autoreceptors, and has been researched as an add-on therapy to various antidepressants, such as clomipramine and the selective serotonin reuptake ...
The time to peak plasma concentration is 43 minutes, and the half-life is 11.6 hours. [34] Unlike most other drugs, phenelzine irreversibly disables MAO. As a result, it does not necessarily need to be present in the blood at all times for its effects to be sustained.
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Its terminal half-life in plasma is 6–11 hours. [3] About 70% is eliminated in urine with 10% unaltered. [ 3 ] The remaining portion is eliminated through feces .
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